Three- Amino Acids

Three- Amino Acids - Lecture Outline Amino acids a)...

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Lecture Outline Amino acids a) importance of ionizable groups-acid base properties b) c) classification--important types of noncovalent interactions that determine protein structure General Structure of an Amino Acid at pH 7.0 COO - Carboxyl group(deprotonated) | Amino group(protonated) H 3 N + --C--H ←α -Carbon | R Side chain Amino acids are optically active The α -carbon is the chiral center of the molecule(except for glycine) Classification: It's all in the R groups! The R group confers unique characteristics to each amino acid: varying in charge, shape, ability to H-bond, hydrophobicity, chemical reactivity. Classification of amino acids based on the chemical nature of their R group The most common scheme is: Nonpolar(hydrophobic) a) aliphatic - refers to a chain oppose to a ring b) aromatic - has double bond Polar(hydrophilic) a) uncharged b) polar, acidic (negative charge, COO - ) c) polar, basic (positive charge, NH 3 + ) Common amino acids
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Three- Amino Acids - Lecture Outline Amino acids a)...

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