Endocrine I

Endocrine I - XXI. Endocrine System I 2011 Compare and...

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XXI. Endocrine System I 2011 Compare and contrast the nervous and endocrine systems Classify hormones by function Classify hormones by structure Compare and contrast steroidal vs. non-steroidal hormones Describe permissiveness Describe the mechanism of action for steroid hormones Describe the mechanism of action for thyroid hormone Describe the Cyclic AMP mechanism of action Describe the PIP 2 mechanism of action Describe the receptor tyrosine kinase mechanism of action Use hormone structure to predict which mechanism of action is utilized Describe feedback control of blood calcium and blood glucose levels (direct feedback control of endocrine gland.) Draw and describe the anatomy of the hypothalamus and pituitary gland, including the hypophyseal portal system Compare and contrast the anterior and posterior pituitary List the hormones of the anterior pituitary and their functions Endocrine System: Role in Homeostasis Endocrine system = communications system Compare / contrast endocrine and nervous systems Neuroendocrine “system” Hypothalamus as neuroendocrine center Compare/Contrast Exocrine & Endocrine Glands Exocrine glands are ducted glands(salivary) Secretions enter ducts Endocrine glands are ductless glands Secretions enter interstitial fluid blood Endocrine System: Role in Homeostasis Neuroendocrine “system” Hypothalamus as neuroendocrine center Fight/flight response is another example Definitions Hormones are blood-borne chemical messengers Endocrine glands = ductless glands Longer acting than transmitters Tiny quantities produce effects! 1
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Neurohormones Hormones secreted by neurons (called “neurosecretory cells”) Target cells/Receptors RECEPTORS define target cells Hormones may be classified by function or structure Classification by function Releasing Hormones and release inhibiting Secreted by hypothalamus Control anterior pituitary hormones TRH Tropic Hormones Secreted by anterior pituitary Control another endocrine gland + its hormone(s) TSH Effector Hormones Exert effects on target cells change body parameters (ex. glucagon) ******FILL IN***** Classification by structure Amino Acid derivatives Protein/Peptide Steroid Amino Acid Derivatives Derived from Tyrosine (“Amine” hormones in Vander) Thyroid Hormones Catecholeamines Derived from Tryptophan Tyrosine derivatives Thyroid hormones Catecholeamines Norepinephrine 2
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Epinephrine Dopamine (= PIH) inhibits prolactin(release inhibiting hormone) Adrenal medulla hormones are NE and EPI NE is also a transmitter (and EPI is released by some neurons too) Dopamine is secreted by anterior pituitary as Prolactin Release-Inhibiting Hormone (PIH) Dopamine is also a transmitter
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Endocrine I - XXI. Endocrine System I 2011 Compare and...

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