Endocrine I

Endocrine I - Endocrine System Ch. 17 Overview of Endocrine...

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1 Endocrine System Ch. 17 1 Overview of Endocrine Glands Learning Outcomes – Be able to: • Compare and contrast the nervous and endocrine systems • Classify hormones by function • Classify hormones by structure • Compare and contrast steroidal vs. non-steroidal hormones Describe permissiveness Describe permissiveness • Describe the mechanism of action for steroid hormones • Describe the mechanism of action for thyroid hormone • Describe the Cyclic AMP mechanism of action • Describe the PIP 2 mechanism of action • Describe the receptor tyrosine kinase mechanism of action • Use hormone structure to predict which mechanism of action is utilized • Describe feedback control of blood calcium and blood glucose levels (direct feedback control of endocrine gland.) • Draw and describe the anatomy of the hypothalamus and pituitary gland, including the hypophyseal portal system • Compare and contrast the anterior and posterior pituitary • List the hormones of the anterior pituitary and their functions 2
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2 Endocrine System: Role in Homeostasis • Endocrine system = communications system communications system • Compare / contrast endocrine and nervous systems (table 17.2) • Neuroendocrine “system” – Hypothalamus as 3 – Hypothalamus as neuroendocrine center •Ex o c r i n e g l a nd s are ducted glands are ducted
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3 Compare/Contrast Paracrine, (See Fig. 17.1 and table 17.3) 5 Endocrine System: Role in Homeostasis • Neuroendocrine “system” Hypothalamus as neuroendocrine – Hypothalamus as neuroendocrine center – Fight/Flight response is another example 6
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4 Definitions • Hormones are blood-borne chemical messengers – Endocrine glands = ductless glands –L o nger acting than transmitters – Tiny quantities produce effects! 7 • Neurohormones – Hormones secreted by neurons (called “neurosecretory cells”) Target Cells / Receptors
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5 Hormones may be classified by function or structure • Classification by function – Releasing Hormone Releasing Hormones • Secreted by hypothalamus • Control anterior pituitary hormones – Tropic Hormones • Secreted by anterior pituitary Controls another endocrine 9 • Controls another endocrine gland + its hormone(s) – Effector Hormones • Exerts effects on target cells Classification by Structure Amino Acid Derivatives Protein/Peptide Steroid 10
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6 Amino Acid Derivatives • Derived from Tyrosine (“Amine” Tyrosine ( Amine hormones in Vander) – Thyroid Hormones – Catecholeamines • Derived from 11 Derived from Tryptophan –Me la ton in Tyrosine derivatives • Thyroid hormones Catecholeamines – Norepinephrine – Epinephrine –D o
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Endocrine I - Endocrine System Ch. 17 Overview of Endocrine...

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