LS2 Lect4

LS2 Lect4 - THE ENDOCRINE SYSTEM Prof Peter Ellison ofFce...

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Unformatted text preview: THE ENDOCRINE SYSTEM Prof. Peter Ellison, ofFce hours M 2-3 Sci Ctr B or by appt. Chapter 7 (pp. 175-218) “transducer” PITUITARY THE ENDOCRINE SYSTEM Prof. Peter Ellison, ofFce hours M 2-3 or by appt. Chapter 7 (plus review ch. 4) LECTURE OUTLINE 1. Types of signals 2. Types of receptors 3. ¡eedback control 4. Hypothalamus and pituitary 5. Example: HPA axis Once upon a time . . . Where is everybody? Food!! Sometime later . . . Let ʼ s PARTY! β ¡ adrenergic receptor The “sensory organs” of single celled organisms provided the foundation for cellular integration in multicellular organisms. THREE MAJOR SYSTEMS OF INTEGRATION NERVOUS SYSTEM Point-to-point, fast, sensory information, muscle control, cognition ENDOCRINE SYSTEM Broadcast, ¡xed source to dispersed targets, coordination of physiology, integration of physiology and behavior, regulation of gene expression IMMUNE SYSTEM Broadcast, mobile sources and targets, detection of “non-self” indicators, coordination of mobile defenses, “search and destroy”, rapid clonal expansion THREE MAJOR SYSTEMS OF INTEGRATION NERVOUS SYSTEM Point-to-point, fast, sensory information, muscle control, cognition ENDOCRINE SYSTEM Broadcast, ¡xed source to dispersed targets, coordination of physiology, integration of physiology and behavior, regulation of gene expression IMMUNE SYSTEM Broadcast, mobile sources and targets, detection of “non-self” indicators, coordination of mobile defenses, “search and destroy”, rapid clonal expansion ENDOCRINE PARACRINE HORMONES KINDS OF HORMONES • short amino acid chains • neurosecretion, cellular secretion • long amino acid chains • glandular secretion BOTH • coded in genome • membrane receptors PEPTIDES oxytocin PROTEINS prolactin KINDS OF HORMONES...
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LS2 Lect4 - THE ENDOCRINE SYSTEM Prof Peter Ellison ofFce...

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