psych106-4

psych106-4 - Lecture 4(Jan 19th SYNAPSES AND DRUGS Lecture...

Info iconThis preview shows pages 1–6. Sign up to view the full content.

View Full Document Right Arrow Icon
Lecture 4 (Jan 19th): SYNAPSES AND DRUGS Lecture Outline 1) Types of Ion Channels - VOLTAGE-gated - NEUROTRANSMITTER-gated - STIMULUS-gated 2) Neurotransmitter (NT) Types 3) A Day in the Life of a NT 4) Two Main Types of NT-gated RECEPTORS - Ionotropic - Metabotropic Caffeine and Alcohol (for you to learn from book, just the basics )
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
CONTROL (OPEN/CLOSE) OF ION CHANNELS 1) Voltage (i.e., Membrane Potential) (last lecture) 2) Neurotransmitter (NT) (today’s lecture) 3) But for the SENSES , the input STARTS with a Stimulus (e.g., LIGHT, SOUND or TOUCH) General Overview of NT Actions: NT Binds to receptors on neuron’s dendrites -> Opens “Neurotransmitter-GATED” Ion Channels -> Change in membrane potential -> If depolarization, and gets to –55 mV -> Action Potential -> travels down axon -> Releases NT at axon terminals into synapse -> and repeat
Background image of page 2
Also, Purines and Gases NEUROTRANSMITTER (NT) TYPES A Day in the Life of a Neurotransmitter (NT)
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
The neurotransmitter needs to GO AWAY! 1b
Background image of page 4
6) The NT needs to go away! a) NT is re-absorbed by the presynaptic terminals, i.e., recycled e.g., Monoamines b) NT is altered (in the synapse) to an inactive state. i) broken down by enzymes e.g., Acetylcholinesterase (AChe): ACh -> acetate + choline choline reabsorbed and added to acetate ii) converted to an inactive state by enzymes e.g., MAO (monoamine oxidase), converts Monoamines to inactive state - drugs that inhibit MAO are used for depression c) Release of more NT is inhibited by activation of
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 6
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

Page1 / 14

psych106-4 - Lecture 4(Jan 19th SYNAPSES AND DRUGS Lecture...

This preview shows document pages 1 - 6. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online