psych106-19

psych106-19 - Lecture 19 (March 13th): Learning and Memory:...

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Lecture 19 (March 13 th ): Learning and Memory: Neural Mechanisms Lecture Outline 1) Hebbian Mechanisms explain Classical Conditioning (and Learning in General) 2) Neural Underpinnings of Hebbian Mechanisms Long-Term Potentiation, LTP and Long-Term Depression, LTD 3) Examples of Hebbian Mechanisms in Visual Cortex (via an l LTP-like z mechanism) 4) Relationship between LTP and Learning/Memory Behavior 5) Non-Associative Neural Mechanisms e.g., Habituation (Aplysia), You can SKIP Sensitization
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Learning = Memory and, whenever we learn something, the BRAIN must be changing! Donald Hebb : Learning must be a change at the synapse Hebbian Mechanism: Increase in synaptic strength (i.e., connectivity) between a PRE- and POST- synaptic neuron when the two neurons are active simultaneously. Or…. l Neurons that fre together get wired together z !
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l Neurons that fre together get wired together z ! CR Training Let ` s revisit Classical Conditioning This is an example For Implicit memory, but this kind oF phenomenon happens For Explicit memories too!
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Demonstrating Hebbian Mechanisms in Neurons in vitro (i.e., in a dish) 1) Measure l baseline z POST-synaptic response to single pulse onto axons of PRE-synaptic neurons.
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psych106-19 - Lecture 19 (March 13th): Learning and Memory:...

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