ch 26 140b - Chapter 26: Amino Acids & Proteins I. Amino...

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I. Amino Acids A. Structure and Properties A.1. Amino acids are carboxylic acids that bear an amine group A.2. Amino acids contain an R group side chains which makes each amino acid different from one another A.3. There are 20 amino acids A.3.a. 8 essential – human body cannot make A.3.b. 12 non-essential – human body can make B. Zwitterion B.1. Amino acid with positive and negative formal charges on different atoms with a total net charge of zero B.2. The overall charge of amino acid in solution depends on the pH B.3. Isoelectric Point (pI): pH at which the extent of protonation equals that of deprotonation B.3.a. Positive charge balances negative charge/maximize net 0 charge (neutral) B.3.b. Concentration of neutralized zwitterions form is greatest B.3.c. pI = pka COOH + pka NH3 /2 B.4. Some R group side chains also have acidic/basic groups which results in another charge state pH <1 pH ≈ 6 pH >13 Acidic Solution Neutral Basic Solution C. Amino Acid Synthesis
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This note was uploaded on 03/27/2012 for the course CHEM 140B CHEM 140B taught by Professor Theodorakis during the Spring '10 term at UCSD.

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ch 26 140b - Chapter 26: Amino Acids & Proteins I. Amino...

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