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The_chemistry_of_life - January 19th 2012 The chemistry of...

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Cell chemistry is hierarchical Inorganic precursors Small organic molecules The chemistry of life BIO 1140 – SLIDE 1 Macromolecules Supramolecular structures Organelles/structures Cell Review of macromolecules Carbohydrates Polymers of monosaccharides (polysaccharides) Energy storage Structural chitin BIO 1140 – SLIDE 2 http://www.mpie.de/index.php?id=2957 Purple pages F23 starch glycogen cellulose Monosaccharides C n H 2n O n n = 3 to 7 Trioses, pentoses and hexoses most common Linear vs ring configuration Asymmetrical C isomers glyceraldehyde ribose BIO 1140 – SLIDE 3 Purple pages F20-21 ß-D-glucose Fig. 2.13 D-glucose -D-glucose January 19th, 2012 -
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Polysaccharides Glycosidic bond C1 to C4 vs ß starch glycogen BIO 1140 – SLIDE 4 Purple pages F22-23 NH C=O CH 3 NH C=O CH 3 NH C=O CH 3 NH C=O CH 3 cellulose chitin Fig. 2.17 Karp 2010 Test your recall: Distinguish between a polymer and a polysaccharide. Provide an example of a carbohydrate used for energy storage. Glucose is a 6-carbon sugar or __________________. Why are there and ß forms of glucose in the ring configuration but not in the linear configuration? What carbohydrate is formed from repeated units of ß-glucose? Can humans digest this carbohydrate? BIO 1140 – SLIDE 5 Nucleic acids Polymers of nucleotides Informational DNA vs RNA Nucleotides 5C sugar – ribose or deoxyribose nitrogenous base Purine: adenine, guanine Pyrimidine: cytosine thymine uracil BIO 1140 – SLIDE 6 H (deoxyribose) Purple pages F29-30 Fig. 4.12 Pyrimidine: cytosine, thymine, uracil Sugar + base = nucleoside Up to 3 phosphate groups nucleotide Several different roles in cell...
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