BIO 1140 – SLIDE #1Unit 2 –Information flowUnit 2 –What explains the variety of systems and their regulation?DNARNAProteinThe Central DogmaReplication Transcription TranslationReadingChapter 13.3,13.4Chapter 14Chapter 15ObjectivesDNA Replication in eucaryotesWhat is a gene?Transcription in eucaryotes Translation in eucaryotesRegulationBIO 1140 – SLIDE #2BIO1140 CELL BIOLOGYExamples of netiquette rules concerning peer respect(from Centre for University Teaching)• Be sure your device sound is set to “off” at the beginning of class• Stay on task. Activities such as Web surfing or gaming may distractclassmates.• Listen to your classmates if they complain to you that your use isdistractingBIO 1140 – SLIDE #3Unit 2 – Information flowGene RegulationWHY IS UNDERSTANDING REGULATION THE KEY TO UNDERSTANDING SO MUCH OF LIFE?Changes in environment or changes in nutrientsChanges in make up of cell is response to signalsIn a multicellular organism, cellular differentiationConserve energyGene regulation refers to the regulation of activity and may occur at any level. While the main control is at the level of transcription additional controls are at the posttranscriptional, translational andposttranslational levels. At the level of transcription, trans-acting factorsInteracting with cis-acting sequences.- tells us how everything is integrated - all of these involve cis acting sequences and trans- if you don't produce the right proteins, or if you don't produce enough... etc in trouble - which is why regulation is important - must be able to respond to changes in enviro or nutrients and respond adequately
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