Chap 3 ppts - Phospholipid structure Amphipathic...

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1 Phospholipid structure Amphipathic molecule (phosphatidyl choline) hydrophobic part: fatty acids hydrophilic part: phosphate & choline
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2 Membrane structure
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3 Membrane components
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4 Transmembrane proteins
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5 Intercellular structures Desmosomes “spot welds”, dense proteins (cytoplasm & intercellular) fibers (intermediate filaments) extend across cells epithelial cells (especially skin), cardiac intercalated disks Tight junctions cell “collar”, block large molecules, no lateral protein movement epithelial cells Gap junctions cell-cell communication, small molecules (<1000 MWt) cardiac intercalated disks, smooth muscle
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6 Desmosomes fig 3-10a “spot welds”, dense proteins (cytoplasm & intercellular) fibers (intermediate filaments) extend across cells epithelial cells (especially skin), cardiac intercalated disks
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7 Tight junctions fig 3-10b cell “collar”, block large molecules, no lateral protein movement epithelial tissue (esp. kidney, gut) paracellular pathway between cells
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Chap 3 ppts - Phospholipid structure Amphipathic...

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