Lecture 21 Cytoskeleton

Lecture 21 Cytoskeleton - Biol141 Foundations in Modern...

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Biol141 Foundations in Modern Biology Cellular Biology and Genetics Lecture 21 – Monday, October 17 th , 2011 Cytoskeleton. Reading: Freeman, Emory 2 nd Ed. Chapter 7
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Learning objectives At the end of this lecture, you will be able to: 1) Describe the interaction of Actin and Myosin motor proteins to generate movement. 2) Compare Actin filaments to Intermediate filaments. 3) Explain the role of microtubules in the vesicular transport and ciliary and flagellar movement.
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1. The cytoskeleton is a complex network of fibers that helps maintain cell shape by providing structural support. 1. 2. 3. The cytoskeleton is dynamic; it changes to alter the cell ` s shape, to transport materials in the cell, or to move the cell itself. The cytoskeleton is a complex network of fibers that helps maintain cell shape by providing structural support.
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The cytoskeleton is made of up three different types of protein filaments 1. 2. 3. Supportive fibers that mechanically reinforce tissues (~10nm diam.) Involved in movement and positioning of organelles and chromosomes during cell division (~25 nm diam.) Involved in motility of entire or parts of cells (~7 nm diam.) Each type of cytoskeletal element differs in terms of size, protein components, cellular location, and function.
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Actin filaments are the smallest cytoskeletal elements. Actin filaments form by polymerization of individual
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This note was uploaded on 04/02/2012 for the course BIO 141 taught by Professor Dr.cafferty during the Fall '11 term at Emory.

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Lecture 21 Cytoskeleton - Biol141 Foundations in Modern...

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