dcWNE9-Lecture 19 Eukaryotic Cells and the Endomembrane system

DcWNE9-Lecture 19 Eukaryotic Cells and the Endomembrane system

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Biol141 Foundations in Modern Biology Cellular Biology and Genetics Lecture 19 – Wednesday, October 12 th , 2011 Eukaryotic cells (continued) and the Endomembrane System Reading: Freeman, Emory 2 nd Ed. Chapter 7 (pages 109-120)
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Learning objectives At the end of this lecture, you will be able to: 1) Draw and describe the location and function of major organelles within the eukaryotic cell. 2) Describe the roles of the RER and the Golgi apparatus for protein secretion. 3) Explain the role of carbohydrate tags in protein transport in the endomembrane system.
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1. The Nucleus is large and highly organized. STRUCTURE: – The nucleus is surrounded by a double-membrane nuclear envelope . – The nucleus has a distinct region called the nucleolus . FUNCTION: – Information storage and processing • Contains the cells chromosomes – Ribosomal RNA synthesis (in the nucleolus)
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Rough Endoplasmic Reticulum STRUCTURE: – The rough endoplasmic reticulum ( rough ER, RER ) is a network of membrane-bound tubes and sacs studded with ribosomes. • The interior is called the lumen . – The rough ER is continuous with the nuclear envelope. FUNCTION: – Ribosomes associated with the rough ER synthesize proteins. – New proteins are folded and processed in the rough ER lumen.
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Smooth Endoplasmic Reticulum STRUCTURE: – The smooth endoplasmic reticulum ( smooth ER, SER ) lacks the ribosomes associated with the rough ER. FUNCTION: – Enzymes within the smooth ER may synthesize fatty acids and phospholipids, or break down poisonous lipids. – Reservoir for Ca 2+ ions
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Golgi Apparatus STRUCTURE: – The Golgi apparatus is formed by a series of stacked flat membranous sacs called cisternae. FUNCTION:
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This note was uploaded on 04/02/2012 for the course BIO 141 taught by Professor Dr.cafferty during the Fall '11 term at Emory.

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DcWNE9-Lecture 19 Eukaryotic Cells and the Endomembrane system

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