Lecture 5 Central Dogma

Lecture 5 Central Dogma - Biol141 Foundations in Modern...

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Biol141 Foundations in Modern Biology Cellular Biology and Genetics Lecture 5 – Friday, August 29 th , 2011 The Central Dogma, nucleotides, and nucleic acids. Reading: Freeman, Emory 2 nd Ed. Chapter 4 (pages 59-66)
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CENTRAL DOGMA CENTRAL DOG
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Learning objectives At the end of this lecture, you will be able to: 1) Explain the “Central Dogma,” that is, the general flow of information from DNA to RNA to Protein. 2) Draw the general structure of a nucleotide and of a purine or pyrimidine base (but do not memorize the structures of the five bases). 3) Describe the polymerization of nucleotides to form nucleic acids with sugar-phosphate backbones, including how energy is provided for nucleic acid polymerization and the location of addition of a nucleotide to a nucleic acid. 4) Explain what evidence led to the discovery of DNA structure, including Chargraff’s Rule, and describe the structure of DNA. 5) Determine the sequence of a DNA or RNA strand given the sequence of a complementary strand.
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These are the terms required to understand the Central Dogma, nucleotides, and nucleic acids: a. nucleotide b. nucleoside c. pyrimidine
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Lecture 5 Central Dogma - Biol141 Foundations in Modern...

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