Lecture 31 Genetics VI

Lecture 31 Genetics VI - Biol141 Foundations in Modern...

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Biol141 Foundations in Modern Biology Cellular Biology and Genetics Lecture 31 – Friday, November 11 th , 2011 Interactions between two genes Reading: Klug. Chapter 4 pages 67-78.
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Learning objectives At the end of this lecture, you will be able to: 1) Explain the genetic concepts of penetrance, expressivity, and pleotropy. 2) Describe examples of epistatic genetic interactions that affect the expected Mendelian ratio of a dihybrid cross (AaBb x AaBb).
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1. Genetic background and the environment affect phenotypic expression. ! Genotype and environment interact to determine the phenotype of an organism. ! Variables such as light, temperature, and nutrition can affect the translation of genotype into phenotype. ! Penetrance is the proportion of individuals in a group with a given genotype that express the corresponding phenotype. ! The expressivity of the genotype is the degree to which it is expressed in an individual.
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Pleiotropic alleles are single alleles that have more than one distinguishable phenotypic effect. ! An example is the
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Lecture 31 Genetics VI - Biol141 Foundations in Modern...

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