Lecture 15 Population genetics III

Lecture 15 Population genetics III - Biol142 Foundations in...

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Biol142 Foundations in Modern Biology II Cellular Biology and Genetics Lecture 15 – Friday, February 20 th , 2012 Population Genetics III. Reading: Klug, Emory 2 nd Ed. Chapter 23 (pages 483-488)
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Today we are examining two types of population genetics problems: 1. Given genotypic freq, determine if in HW equilibrium . 2. Assuming HW equil ., calculate allele and/or genotypic frequencies from phenotypic frequencies.
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The Hardy-Weinberg law describes what happens to alleles and genotypes in an “ideal” population. ! Our in-class “mass-mating” experiment approximated many of the conditions assumed by the Hardy-Weinberg law. 1. Males and females mate randomly. 2. Natural selection does not affect the alleles under consideration. 3. A large population (eliminates sampling error). 4. There is no migration between populations. (i.e. gene flow) 5. There is no mutation. ! The Hardy-Weinberg law assumes: Violation of any of the above conditions results in a change in allele frequency from one generation to the next.
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conditions of the Hardy–Weinberg equilibrium are met , two results follow. 1. The frequencies of alleles at a locus will remain constant from generation to generation. After one generation of random mating , the genotype frequencies will not change
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This note was uploaded on 04/02/2012 for the course BIO 142 taught by Professor Escabar during the Spring '08 term at Emory.

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Lecture 15 Population genetics III - Biol142 Foundations in...

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