Ch11Bio - Chapter 11 DNA and Its Role in Heredity Smooth...

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Chapter 11, page 1 Chapter 11 DNA and Its Role in Heredity Smooth polysacchrides lipids RNA proteins mix each with rough cells, assay in mice only DNA fraction had transforming ability DNA
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Chapter 11, page 3 DNA T2 bacteriophage protein
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Chapter 11, page 4 DNA structure O CH 2 OH CH OH CH OH CH OH CH 1. Thread, 20 Angstroms thick 2. Helical, turn 34 angstroms 3. Stack, every 3.4 angstroms
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Chapter 11 Highlights: I. DNA: The Genetic Material A. DNA from one type of bacterium genetically transforms another type B. The transforming principle is DNA C. Viral replication experiments confirm that DNA is the genetic material II. The Structure of DNA A. X-ray crystallography provided clues to DNA structure B. The chemical composition of DNA was known C. Watson and Crick described the double helix D. Four key features define DNA structure E. The double helical structure of DNA is essential to its function III. Determining the DNA Replication Mechanism A. Three modes of DNA replication appeared possible B. Meselson and Stahl demonstrated that DNA replication is semiconservative IV. The Molecular Mechanisms of DNA Replication A. DNA is threaded through a replication complex B. Small, circular DNAs replicate from a single origin C. Large, linear DNAs have many origins D. DNA polymerases need a primer E. Cells contain several different DNA polymerases F. The lagging strand is synthesized from Okazaki fragments G. Telomeres are not fully replicated V. DNA Proofreading and Repair A. Proofreading mechanisms ensure that DNA replication is accurate B. Mismatch repair mechanisms correct base-pairing errors C. Excision repair mechanisms repair chemical damage VI. Practical Applications of DNA Replication
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Ch11Bio - Chapter 11 DNA and Its Role in Heredity Smooth...

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