BIO1140 Study Group #5 Answer Key

BIO1140 Study Group - BIO1140 Study Group#5 Answer Key 1 Describe the various elements of the cell-signaling system i Signaling molecule(rst

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BIO1140 Study Group #5 Answer Key 1. Describe the various elements of the cell-signaling system. i. Signaling molecule (Frst messenger) ii. Reception Receptor – membrane, cytosolic or nuclear iii. Transduction Signalling cascades and second messengers iv. Response Changes in gene expression Changes in activities of enzymes, transcription factors or other regulatory proteins, transporters, cytoskeleton etc v. Termination 2. Describe the structure of membrane receptor signaling systems (i.e. the different domains, the different types of membrane receptors, etc.) Ligand binding domain Transmembrane domain Intracellular domain (catalytic domain) Inactive receptor Active receptor
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Signals are water-soluble chemicals Signalling molecule does not enter cell Signal removal e.g. environmental chemicals, neurotransmitters, hormones Membrane receptors are integral membrane glycoproteins Ligand-gated channels Receptor tyrosine kinases G protein-coupled receptors 3. What happens in signaling cascades?
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This note was uploaded on 03/30/2012 for the course SCIENCE BIO1140 taught by Professor Fenwick during the Spring '09 term at University of Ottawa.

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BIO1140 Study Group - BIO1140 Study Group#5 Answer Key 1 Describe the various elements of the cell-signaling system i Signaling molecule(rst

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