Lecture_13_handout

Lecture_13_handout - nuclear envelope? How do you target...

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cytosol RanGTP Ran GDP Exportin Ran GAP Ran GEF Ran GTP Free nuclear protein NLS protein Importin α Importin β Cytoplasmic filament Nucleus Nuclear Pore Complex envelope Inside nucleus Nuclear pore complex (NPC) ER ONM INM lamin
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How do you transfer force across the two membranes of the
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Unformatted text preview: nuclear envelope? How do you target proteins to the outer or inner nuclear membrane? UNC-83 KASH domain SUN domain UNC-84 ONM INM Lee et al. 2002 Anti-UNC-84=Red DNA=Blue UNC-83=Red DNA=Blue Cell-Cell boundary=Green From Starr and Fridolfosson 2010. pdf on Smartsite...
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Lecture_13_handout - nuclear envelope? How do you target...

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