ProblemSet10

ProblemSet10 - might these physiological changes result in...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
BC367, Fall 2011 Problem set #10 Due: Friday, December 2 nd (HandAin problems must be done on separate pages. ±ll short answer questions must be typed.) Before completing this assignment, please read the article attached to the wiki by Vaziri. The following questions are based on that article. 1) Do normally functioning kidneys specifically participate in lipid metabolism? Do the empirical symptoms of kidney disease specifically involve dysregulation of lipid metabolism (dyslipidemia)? What are the two primary sources of serum lipids? How are lipids stored / transported in human blood serum? 2) Consider the biochemical consequences of a decline in kidney function. How
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: might these physiological changes result in an increased concentration of serum lipids? 3) In addition to the dysregulation of lipids derived from fatty acids, an upregulation of HGMCoA reductase is often found in patients with chronic kidney disease. What does this cause? How could it be treated? 4) It is possible (if not likely) that dyslipidemia can further the progression of kidney disease. However, of even greater concern is the observation that dyslipidemia associated with kidney disease can increase a patients risk of cardiovascular disease. Consider how this is possible and how the risks differ from the normal population....
View Full Document

Ask a homework question - tutors are online