BIO220-Slides-Lecture8-W2012(1)

BIO220-Slides-Lecture8-W2012(1) - Deadly Viruses & The...

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1 Deadly Viruses & The Evolution of Virulence
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Virulence Evolution Examples – the problem Conventional Wisdom Parasite Adaptation • explicit theory • verbal theory (Ewald)
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3 • March, 1918 – a few dozen WWI recruits came down with the flu • As these soldiers were mobilized they spread the virus quickly to other soldiers • Confined and heavily populated living quarters led to an increasing epidemic • By September 1918 it had become increasingly virulent 1918 Influenza Epidemic
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Between September and December 1918 thousands of otherwise healthy young adults (20 to 45 years old) died By 1919 about 30-50 million people were killed Then this influenza virus seemed to vanish
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5 Influenza • Most current flu viruses are not particularly virulent • The 1918 flu strain was WHY?
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6 Ebola virus • Causes Ebola hemorrhagic fever, a severe and often fatal disease • Spread by direct contact with contaminated material and possibly through air • High fever, headache, stomach and chest pain, vomiting, and severe internal bleeding
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7 In 1976 the first Ebola outbreak in humans occurred in Zaire and Sudan (~500 cases) and then disappeared In 1989 Ebola appeared again in monkeys imported into Virginia, USA In 1994-96 Ebola appeared once again in Africa at five different locations Ebola virus
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8 Distribution of Ebola Virus WHY?
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This note was uploaded on 04/03/2012 for the course EEB BIO220 taught by Professor Locke during the Spring '12 term at University of Toronto- Toronto.

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BIO220-Slides-Lecture8-W2012(1) - Deadly Viruses & The...

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