01HWF11_Key

01HWF11_Key - BSCI410/HW#1/SP10 BSCI 410-Liu/Chang...

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Unformatted text preview: BSCI410/HW#1/SP10 BSCI 410-Liu /Chang Homework#1 Fall 2011 Due: Tu (Sept. 20) at 11:00 AM in class 1. (5 points) Multiple choices (pick one) (1). Which type of mutation is least likely to revert? (a) Deletion ; (b) Translocation ; (c) transposition; (d) transition; (e) a and b (2). The hydrolysis of an -NH2 group from a base is called (a) hydroxylation; (b) alkylation; (c) deamination ; (d) intercalation (3). The fluctuation test of Luria and Delbruck established that: a) Bacterial resistance to phages and other bactericides is the result of mutations. b) Mutations arise as a directed response to environmental change. c) Mutations occur spontaneously as a result of random processes that can happen at any time and anywhere in the genome. d) In E. coli , the number of mutants per tube was relatively constant. e) a and c (4). In an Ames test for mutagenicity, rat liver enzymes are accidentally excluded from the compound under test. What can you say about the result? a) the mutation rate will probably rise b) the mutation rate will probably decline c) the results are less relevant to mammals d) the results are less relevant to bacteria e) no mutations will form (5). To isolated mutants in essential genes (genes absolutely needed for survival), we need to isolate a) mutations that only partially disrupt the function of the gene b) mutations that are transition mutations c) mutations that disrupt the gene function only under certain conditions d) mutations that can be reverted e) a and c...
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01HWF11_Key - BSCI410/HW#1/SP10 BSCI 410-Liu/Chang...

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