midterm+1+parctice

midterm+1+parctice - Midterm I practice exam Instructions:...

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Midterm I practice exam 1 Instructions: Note that this is last year’s midterm 1. Not all material was covered in exactly the same way. Fill out your student ID properly. If you make a mistake in filling out the student ID, you will be docked 5 points. There are 10 pages and 35 questions to this exam DO NOT OPEN UNTIL INSTRUCTED. The exam will end promptly at 9:50 am. If you think there is an error in the exam, notify the professor or TA. We can’t help you define terms or clarify wording. Always pick the best answer. For each question there is one, best correct answer. Fill out your name and student identification number on the blue Scantron Form with a #2 pencil. Fill in your answers on the scantron form with a #2 pencil. For each question only choose one answer (the best answer) and fill in you selection clearly and completely. If you change an answer, make you sure you erase it completely. There are 35 questions. 30 are worth 3 points and 5 (indicated) are worth 2 points, for a total of 100 possible points.
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Midterm I practice exam 2 1. From your reading in problem set two on the molecular anatomy of a vesicle, which of the following are true? A. A vesicle has only one kind of v-SNARE and only one kind of Rab to bind to a specific membrane. B. More of the surface area of a vesicle is covered by lipids than proteins. C. To purify vesicles, triton-X-100 is used. D. More than half of the Rabs in the genome are on this type of vesicle. E. The uniform vesicles studied were of the COP II variety. 2. You remove a KKVI sequence from the C-terminus of the KDEL receptor. Where would you now find BiP (normally in the ER)? A. In the ECM B. In the ER C. In the cytoplasm D. In the Golgi E. In the lysosome 3. You can therefore conclude from question #2 that the KKVI sequence is _______ for the localization of BiP to the ER. A. Necessary B. Sufficient C. Necessary and sufficient D. Neither necessary nor sufficient E. Impossible to conclude 4. You isolate digestive enzyme Q that is normally secreted form pancreatic acinar cells. You add a “stop transfer” signal of 20 hydrophobic amino acids to the middle of the enzyme Q protein sequence. Where will the C-terminus of this new protein be? A. The ER lumen B. The outside the cell C. The cytoplasm D. The cis-Golgi E. It will be degraded 5. Glucose is moved into intestinal epithelial cells against its concentration gradient using __________, and exits the cell into the blood using _____________. A. Glucose ATPase; gated channel B. Na+ symporter; Na+ antiporter C. Na+ antiporter; glucose channel D. facilitator; facilitator E. Na+ symporter; facilitator
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Midterm I practice exam 3 6. BiP is normally a component of the ER lumen. You delete the last (C-terminal) four amino acids of BiP. Where would you now predict the majority of BiP to now localize? A. The ER
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This note was uploaded on 04/03/2012 for the course BIS BIS 104 taught by Professor Privalsky during the Spring '09 term at UC Davis.

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midterm+1+parctice - Midterm I practice exam Instructions:...

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