Microbial Metabolism-Enzymes-sp10

Microbial Metabolism-Enzymes-sp10 - Specificity of active...

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MICROBIAL METABOLISM ENZYMES CHAPTER 5
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Metabolism : sum of all chemical reactions within an organism. Metabolism: 1. Anabolism: 2. Catabolism:
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Metabolic Reactions • A metabolic pathway is a sequence of enzymatically catalyzed chemical reactions in a cell which are determined by enzymes. 1. Exergonic 2. Endergonic
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Enzymes: Biological catalysts Protein in nature Reaction runs 8-10 billion times faster
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Figure 5.2 Energy Requirements of a Chemical Reaction
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Enzyme Structure Holoenzyme 1. Apoenzyme 2. Cofactor 1) Coenzymes: NAD + , FAD, CoA 2) Metal ions
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Figure 5.3 Components of a Holoenzyme
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Mechanism of Enzymatic Action Active site of an enzyme Enzyme-substrate complex
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Unformatted text preview: Specificity of active site Figure 5.4a The Mechanism of Enzymatic Action Relationship between Enzyme Structure and Function 1 , 2 , 3 0 and 4 0 structure of an enzyme Change of enzyme shape Change of active site----denaturation Factors affecting enzymatic activity Temperature pH Substrate concentration Inhibitors Figure 5.5a Effect of Temperature on Enzyme Activity Inhibitors Competitive inhibition Noncompetitive inhibition Figure 5.7ab Enzyme Inhibitors: Competitive Inhibition Enzyme Inhibitors: Competitive Inhibition Figure 5.7a, c Enzyme Inhibitors: Noncompetitive Inhibition...
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Microbial Metabolism-Enzymes-sp10 - Specificity of active...

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