09-4 nucleic acid

09-4 nucleic acid - Macromolecules Large molecules of polymerized subunits Proteins or polypeptides amino acid subunits Polysaccharides sugar

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Macromolecules Large molecules of polymerized subunits: Proteins or polypeptides: amino acid subunits Polysaccharides: sugar subunits Nucleic acids: nucleotide subunits RNA: ribonucleotide subunits DNA: deoxyribonucleotide subunits
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Nucleotides Building blocks of nucleic acids (DNA, RNA) Three components: Phosphate group Pentose (5-carbon) sugar: ribose (RNA) or deoxyribose (DNA) Nitrogenous bases: Purines: adenine (A) and guanine (G) Pyrimidines: cytosine (C), uracil (U in RNA) and thymine (T in DNA) 2’-Carbon position: critical to functional differences between RNA and DNA!
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Nitrogenous Bases
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Nucleotide Polymerization Condensation reactions via covalent phosphodiester bonds Ribonucleotide polymers form ribonucleic acid or RNA Deoxyribonucleotide polymers form deoxyribonucleic acid or DNA Nucleic acids have polarity: 5’-phosphate terminus, 3’-OH (hydroxyl) terminus
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Nucleic Acids - RNA Strong phosphodiester backbone
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This note was uploaded on 04/05/2012 for the course HLTH 311 taught by Professor Anderson during the Spring '12 term at BYU.

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09-4 nucleic acid - Macromolecules Large molecules of polymerized subunits Proteins or polypeptides amino acid subunits Polysaccharides sugar

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