09-3 amino acid protein 09 (1)

09-3 amino acid protein 09 (1) - Macromolecules Large...

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Macromolecules Large molecules of polymerized subunits: Proteins or polypeptides: amino acid subunits Polysaccharides: sugar subunits Nucleic acids: nucleotide subunits RNA: ribonucleotide subunits DNA: deoxyribonucleotide subunits
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Amino Acids: building blocks of proteins 20 that comprise proteins Three parts: Amino group (NH 2 -) Carboxyl group (COOH-) Functional side chain (R-) Determines pH (acidity/alkalinity) Determines charge (-/+) Two contain sulfur atoms Each has a one-letter abbreviation
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Amino Acid Categories Hydrophobic – R groups do not interact with water Associated with membranes Hydrophilic – R groups interact readily with water Basic (alkaline) – R groups attract H + ions in aqueous solution Acidic – R groups lose H + ions in aqueous solution Sulfur-containing Aromatic – R groups have ring structures
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Amino Acid Categories sulfurous hydroxyl (OH)
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Amino Acid Categories (cont’d) acidic
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Amino Acid-Water Interactions Relative water solubility of side chains (R-groups)
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