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BIO 317 - Lec 10 (Intro to Signal Trans)

BIO 317 - Lec 10 (Intro to Signal Trans) - 10 Adrenaline...

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10/5/11 1 Signal Transduction Mechanisms Underlying Intercellular Communication Chemical messengers How are signals generated? How are signals perceived by recipient? How does the signal generate the response? Signal Transduction
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10/5/11 2 Neurotransmitters
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10/5/11 3 Dopamine and Parkinson’s Disease Hormones
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10/5/11 4 Hormones - can they help?
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10/5/11 5 Growth Factors
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10/5/11 6 Mighty Cow Cytokines
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10/5/11 7 Lance Armstrong Erythropoietin (EPO) ? Growth Hormone ? Olfaction Gustation Vision
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10/5/11 8 acetylcholine
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10/5/11 9 Regulation of chemical messengers involves synthesis, packaging, secretion, degradation Regulation is part of the response to stimuli
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Unformatted text preview: 10/5/11 10 Adrenaline Rush 10/5/11 11 1. How does a chemical messenger mediate a response in a particular cell type? 2. How does a chemical messenger mediate a pleiotropic response? 3. How can a single chemical messenger mediate different responses in different targets? How is the chemical signal perceived? Receptors and Pharmacology 10/5/11 12 1. Fast Signaling 2. Binding correlates well with response Direct Receptor Indirect Receptor 1. Slow Signaling 2. Binding does not correlate well with response 10/5/11 13 Integration of signals...
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