B150mW06

B150mW06 - BICD 150, Endocrinology Winter, 2006 February...

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BICD 150, Endocrinology Name: _________________________________ Winter, 2006 Midterm Exam I.D. #: _________________________ February 10, 2006 Page 1 1. (20 points) Match the letter of the corresponding receptor type to the description. There can be multiple receptor types per description. (If none of the choices match the description write “n”) a. Gs - coupled e. Growth Factor Receptors b. Gq - coupled f. Steroid Receptors c. Gi - coupled g. Cytokine Receptors d. Thyroid Receptors Have a single transmembrane domain ____ Located inside the cell _ Decrease intracellular cAMP concentrations when activated Activation can cause smooth muscle contraction Activation causes breakdown of phosphatidylinositol Include the receptor for growth hormone Include the receptor for insulin Bind heat shock proteins Activation causes calcium release from the endoplasmic reticulum Can be located in the nucleus in the absence of hormone __ Must dimerize in order to have activity Have zinc fingers Activation causes tyrosine phosphorylation cascades 2. (14 points). Certain cells stop responding to hormone stimulation after continuous exposure to high
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B150mW06 - BICD 150, Endocrinology Winter, 2006 February...

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