Week 8 Handout Answers

Week 8 Handout Answers - Week 8 Handout TA: Manely Leilah...

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Week 8 Handout TA: Manely Leilah Yafeh 1. List the main symptoms of Type 1 Diabetes. What are the main differences between Type 1 and Type 2 Diabetes?
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2. What treatment options are available for Type 1 and Type 2 Diabetes? What is the purpose of testing for glycated hemoglobin levels? Drug Class Effect Mechanism of Action Sulfonylureas and Meglitinides Stimulate insulin secretion Block K ATP channels α-Glucosidase Inhibitors Decrease intestinal glucose uptake Inhibit disaccharidases Biguanides (e.g. Metformin) Decrease hepatic gluconeogenesis Activate protein kinase PPAR Activators ("Glitazones") Adiponectin, Resistin Activate PPARγ Incretin (GIP, GLP-1) Analogs plasma glucose and weightloss Insulin Glucagon Dipeptidyl peptidase-4 (DPP-4) Inhibitors insulin secretion and gastric delay Half-life of incretins Glycated hemoglobin levels give long-term measure of blood glucose levels in a period of six months.
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Week 8 Handout Answers - Week 8 Handout TA: Manely Leilah...

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