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Week 90 - Week9 Handout Type1diabetes ,...

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Week 9  Handout Type 1 diabetes May develop ketoacidosis, if there is not enough insulin action Increase in glucose concentration -> inc glucosuria -> polyurea -> dehydration  Increase urine -> Drops blood pressure -> tachycardia (accelerated heart rate)->  circulatory shock -> death Inc Beta oxidation of fatty acids -> increase of ketones -> pH drop -> acidosis  Acidosis causes CNS depression -> loss of consciousness Acidosis also can cause hyperventilation May overdose on insulin to develop hypoglycemia If blood glucose falls below 60-70mg/dl  Will cause people to become sleepy, irritated, inc sympathetic response 30-40mg/dl strong sympathetic response increase tachycardia sweating confusion vasoconstriction inc blood pressure loss of consciousness <30mg/dl seizures  death Type 2 diabetes Distinguished from type 1 diabetes, is that these people have functional beta cells in  pancreas
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