Homework03_KEY

Homework03_KEY - BIS101/Draper Homework01_KEY 2. (12 pts)...

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BIS101/Draper Homework01_KEY 2. (12 pts) After determining how may genes you have identified in the life-span screen, you turn your efforts to mapping the genes onto the worm genetic map. You start with the first complementation group that you have designated to be mutant alleles of the gene you now call age-1 . Your preliminary mapping has determined that age-1 maps to linkage group II of the nematode genome. You next use three-factor mapping to refine the map position of age-1 on LG II. Your preliminary results suggest that age-1 is likely to map between the mutations dpy-5 (a recessive mutation that results in “dumpy” (i.e. short and squat) worms, and unc-11 (a recessive mutation that results in “uncoordinated” worms). The three point testcrosses you perform is as follows: Cross: female dpy + unc age+ X dpy unc age male dpy unc + age dpy unc age The results of this test cross are as follows: wild-type 121 dpy 4 dpy age 999 dpy unc 53 dpy unc age 117 unc 991 unc age 3 age
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Homework03_KEY - BIS101/Draper Homework01_KEY 2. (12 pts)...

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