Lecture16-S11 - genomics James D Watson Pacific...

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BIS 101 26 May 11 Final Review Session: Friday June 3 2:10- 4:00 pm Kleiber 3 Draper’s Office Hour NEXT week : Wednesday, June 1 2:00-3:00pm Life Science Rm. 3002 Friday, June 3 3:00-4:00pm Science Lab 3061
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Automated DNA Sequencing
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Whole Genome Shotgun approach: 1) Sequence 2) Assemble map from overlapping sequence
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Figure 12-6
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Figure 12-5
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rdered Clone Sequencing: Map large clones Sequence subclones
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Figure 12-14
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Figure 12-15
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2007 : First individual genome sequence published Independent sequence and assembly of the six billion base pairs from the genome of one person ushers in the era of individualized
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Unformatted text preview: genomics. James D. Watson Pacific Bioscience >10,000 bp reads 2006: Decoding the Neanderthal Genome 8 May 2008 Archaea Eucaryota Bacteria Figure 12-9 Figure 12-1 Figure 12-10 Figure 12-12 QuickTimeª and a TIFF (LZW) decompressor are needed to see this picture. Figure 12-9 Figure 12-19 Protein Binding Sites in Genome Figure 12-20 Mapping Genes in the Genomic Sequence mouse chicken frog zebrafish krox20 krox20 :GFP transgenic krox20 Expression of endogenous (mRNA in situ) Expression of GFP transgene...
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