Lecture17-S11

Lecture17-S11 - BIS 101 31 May 11 Drapers Office Hour NEXT...

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BIS 101 31 May 11 Final Review Session: Friday June 3 2:10- 4:00 pm Kleiber 3 Draper’s Office Hour NEXT week : Wednesday, June 1 2:00-3:00pm Life Science Rm. 3002
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Figure 12-10 Mapping with Molecular Markers
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Figure 12-12 Mapping with Molecular Markers
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QuickTimeª and a TIFF (LZW) decompressor are needed to see this picture. Mapping with Molecular Markers
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Figure 12-9
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Figure 12-19 Bioinformatics: Protein Binding Sites in Genome
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Figure 12-20 Bioinformatics: Mapping Genes in the Genomic Sequence
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mouse chicken frog zebrafish Conserved Gene function
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krox20 :GFP transgenic krox20 Expression of endogenous (mRNA in situ) Expression of GFP transgene Using Transgenics to Define Gene Regulatory Elements
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Point mutations can alter splicing
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Non-conservative Missense Mutations Can Alter Protein Function
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Non-conservative Missense Mutations Can Alter Protein Function
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Molecular Analysis of Mutations
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Rare tautomeric forms that are prone to mismatch (Pyrimidine forms) Normal Missmatched bases Spontaneous Mutations
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(Purine forms) Missmatched bases Spontaneous Mutations Rare tautomeric forms that are prone to mismatch Normal
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Depurination (mammalian cells lose 10,000 purines/20hr cell cycle) Spontaneous Mutations
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Spontaneous Mutations
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This note was uploaded on 04/05/2012 for the course BIS 101 taught by Professor Simonchan during the Spring '08 term at UC Davis.

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Lecture17-S11 - BIS 101 31 May 11 Drapers Office Hour NEXT...

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