Summary slide for MAP CO and TPR 020912

Summary slide for MAP CO and TPR 020912 - body” And how...

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1. Mean arterial pressure= Cardiac output X total peripheral resistance (both important) MAP sensed and tightly controlled: needs to be high enough to efficiently drive blood into tissues and back to heart but not too high MAP too high (hypertension)=> damage vessels, stroke etc. MAP too low (hypotension)=> inadequate driving force for delivery of blood to tissues and back again to the heart (deprive tissues of O 2 , nutrients, hormones, don’t remove CO 2 , wastes etc) A. Cardiac output= Stroke volume X Heart rate (recall how this is regulated) B. Total peripheral resistance: Due to blood viscosity, length of vessels, vessel diameter Additional consideration for delivery of blood to the brain, and venous return from the body: gravity What do we mean by the statement that “arterioles are the major resistance vessels of the
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Unformatted text preview: body”? And how is resistance regulated to help regulate MAP? And can you use the properties of arterioles to selectively increase or decrease blood flow to certain tissues at certain times, with the same MAP? Overview of last lecture (2/8/12): What section shows the biggest mean pressure drop? (But: can’t be too steep or too shallow. .and shouldn’t start too high or too low) Fig. 10 ‐ 9, p. 352 Since: F = Δ P R Good range of pressures for function of (delicate) capillaries Then still enough “oomph” to get back to heart (venous return) Constantly monitored by body via “baroreceptors” in aorta and carotid arteries supplying brain...
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  • Spring '08
  • Fuller,Charles/Goldberg,Jack
  • Back to Bedlam, ARIA Charts, Grammy Award for Album of the Year, total peripheral resistance, Mean arterial pressure=

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Summary slide for MAP CO and TPR 020912 - body” And how...

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