Endocrine system Intro lectures 28 and 29 w12 for slides

Endocrine system Intro lectures 28 and 29 w12 for slides -...

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The Endocrine System Part I: Introduction to the Endocrine System Lectures 28-29 Recommended reading: Sherwood 7 th edition Chapter 4 pp. 113-129 Chapter 18 pp. 661-670
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Topics to be covered in these lectures: General overview of endocrine cells and glands Types of intercellular communication Comparison of the nervous and endocrine systems Nervous system and endocrine system interactions Hydrophilic versus Lipophilic hormones Subclasses of hydrophilic and lipophilic hormones 1. Amino acid derivatives Amines Thyroid hormones 2. Peptide hormones 3. Steroid hormones Chemical properties of a hormone impacts storage, transport, metabolism, excretion, and mode of action at target cells 1. Secretion versus storage 2. Transport 3. Metabolism 4. Action of hormones at target cells: Properties of hormone receptors Membrane receptors: second messenger pathways Example: adrenergic receptors Steroid and thyroid hormones act via nuclear receptors One hormone can influence activity of another hormone How endocrine disorders arise
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Fig. 4-20, p. 114
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Hormones are secreted from individual cells within organs or cells organized into a distinct gland • Overall functions of the endocrine system – In concert with autonomic nervous system, control and integrate the digestion and absorption of food – Regulate organic metabolism and H 2 O and electrolyte balance – Induce adaptive changes to help body cope with stressful situations – Promote smooth, sequential growth and development – Regulate red blood cell production – Control reproduction Fig. 18-1, p. 662
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Comparison of the nervous and endocrine systems
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The Nervous System and the Endocrine System Interact Extensively 1. Neurons secrete hormones (Neurohormones) 2. Secretion of hormones by some cells controlled by nervous system 3. Hormones can affect Birth of new neurons Death of neurons Synapse formation Dendritic branching Membrane potential Myelination of neurons Glial cell number/function 4. Some chemical messengers can act as neurotransmitters OR hormones
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Two distinct groups of hormones based on their solubility properties 1. Hydrophilic hormones • Highly water soluble : Low lipid solubility 2. Lipophilic hormones • Highly lipid soluble: Low water solubility Chemical properties of a hormone impacts: If it can be stored in cells before release into bloodstream
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This note was uploaded on 04/05/2012 for the course NPB 101 taught by Professor Fuller,charles/goldberg,jack during the Spring '08 term at UC Davis.

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Endocrine system Intro lectures 28 and 29 w12 for slides -...

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