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101_12AI_neuro_4-spikes_1

101_12AI_neuro_4-spikes_1 - neurons can… thus neurons...

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Unformatted text preview: neurons can… thus, neurons have… rest leak (&, in some cells, other) channels transduce stimulus energy into electrical signals stimulus-gated channels generate a spike voltage-gated Na & K channels release neurotransmitter onto other neurons & onto other tissues (muscle, etc) voltage-gated Ca channels respond to input from other neurons transmitter-gated channels transduce stimuli process signals produce involuntary responses generate & control behavior extract information & intellectual activity overall functions afferent & efferent signals receptor ending, dendrite, axon, terminal, polarity, rest, response, neurotransmitter 4 cells “responding” 1 2 3 4 formation of extracellular fluid in periphery & in CNS last week Na-K ATPase concentration gradients K-channel leak selectivity voltage gradient electrochemical equilibrium Nernst equation equilibrium potential membrane potential in other words, we have examined: single cells & leak ion channels leak channels stimulus-gated channels transmitter-gated channels voltage-gated channels (Na, K, Ca) input- gated spike- generating transmitter- releasing these channels allow E m to change next, look at single cells with other types of ion channels over the next few lectures, we will learn how this happens Zigmond et al 99 Fundamental Neuroscience, Fig 6.3 neurons can… thus, neurons have… rest leak (&, in some cells, other) channels transduce stimulus energy into electrical signals stimulus-gated channels generate a spike voltage-gated Na & K channels release neurotransmitter onto other neurons & onto other tissues (muscle, etc) voltage-gated Ca channels respond to input from other neurons transmitter-gated channels transduce stimuli process signals produce involuntary responses generate & control behavior extract information & intellectual activity overall functions 4 cells “responding”...
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101_12AI_neuro_4-spikes_1 - neurons can… thus neurons...

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