{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

Updated notes for respiratory system Lecture 27

Updated notes for respiratory system Lecture 27 -...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Hypoven(la(on: pCO2 higher, results in higher H+ =lower pH (acidosis) Hyperven(la(on: pCO2 lower, results in lower H+ =higher pH (alkalosis) Fig. 13 ­31, p. 487 Chemical factors that play role in determining magnitude of ven(la(on (keeping the others constant) Slide 6, lecture 27 NOTE ­ challenges made In arterial blood but venBlaBon Is response of the whole system For example, from what I showed you later, varying CO2 is influencing venBlaBon primarily via diffusion into the brain ECF, geKng converted there to carbonic acid, and the resulBng H+ is influencing CO2 has weak sBmulatory effects on both peripheral and central chemoreceptors which is consistent with what is being shown here. It also shows that arterial H+ changes can be sensed directly by peripheral chemorectors but this can come from anything that changes blood pH not just changes in pCO2. Why isn t a fall in PO2 more of a dominant player here? Recall the Hb-O2 dissociation curve….. NOTE: under normal circumstances, the pO2 of the large arteries(where peripheral chemoreceptors are) is close to pO2 at pulmonary capillaries ...
View Full Document

{[ snackBarMessage ]}