Lecture 9 - • Ganglioside lipid specific sugars o...

Info icon This preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
Lecture 9: C u by natural spontaneous deamination Or DNA polymerase can mistakenly insert uracil into DNA (as DUTP) Many chemotherapeutic drugs affect the cell so it increases dUTP that goes into DNA If dUTP concentration is increased (by drugs) there will be a high level of uracil in DNA and therefore high degree of repair Therefore system overwhelmed DNA fragmentation cell dies Target fast growing/diving cells like cancer Retorius polymerase are highly matagenic Slide Eukaryotic cells Basil body not organelle but in text book is discussed as one Membrane organelle: membrane bound compartments in a cell with a specific function with a degree of permanence, function is usually metabolic
Image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: • Ganglioside lipid + specific sugars o Gangliosides are found in high concentration on nervous tissue membrane • Plasma – allws cell-cell communication • ECM (extracellular matrix)– surface layer surrounds cell ie. Glycocalyx ~ large polysaccharides proteins, proteglycans (allow cells to move past each other or have flexibility ie cartlidge) • Signal transdunction = external signal ex. Hormone or a cytokine that binds to a cell membrane or plasma membrane receptor that then induces a molecular cytoplasmic signal to be made and therefore will affect the inside of the cell (ie. Turn protein or genes on and off) o Transfer of a external signal into an internal signal •...
View Full Document

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern