Section3-1-1 - The Stimulus Nociceptors free nerve endings...

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3/1/12 1 Nociceptors: free nerve endings Activated by various chemicals; i.e chemoreceptors Send info to spinal cord (spinothalamic) The Stimulus Many analgesics work by blocking the formation of these chemicals Anti-histamines: receptor antagonists. Relieve itch Aspirin, ibuprofen: prevent production Olfaction Olfaction: The sense of smell Gustation: The sense of taste Odor: A general smell sensation of a particular quality Odorant: Any specific aromatic chemical Olfactory Stimuli Must be volatile (easily vaporized) Primaries? Unclear if and how many Perception related to chemical structure Function Approach/Avoidance Additional ‘Social’ Role (pheromones) Axel and Buck Press Release Stimuli Stimuli: Odorants (chemicals) Chemical structure is important (green pepper) Not all chemicals are detected; Not all chemicals are “odorants” 1. Volatile molecules enter nasal passages Olfactory Transduction 2. Molecules travel through mucosa Some are “carried” to olfactory receptors by odorant binding proteins.
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