11 25 thus if you are a small molecule say atp or adp

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Unformatted text preview: embrane (fig. 11-25). Thus, if you are a small molecule (say, ATP or ADP) you can move freely between the cytoplasm and the IMS, so the IMS has a similar composition to the cytoplasm. (2) The inner mitochondrial membrane is very different: it has a very high protein content, ￿75% protein and, like bacterial membranes, has no cholesterol. The integral membrane proteins include a variety of transporters, the proteins of the electron transport chain, and ATP synthase. The inner membrane is also very impermeable to solutes but has numerous transporters to manage the exchange of specific molecules between the MATRIX and the IMS. The inner membrane is also deeply and variably infolded, giving it a large surface area relative to the size of the mitochondrion. <Which stages of the total oxidation of glucose occur in mitochondria, and how are they organized?> II. The TCA Cycle (everything here occurs in the mitochondrial matrix; see DVD 13-2!) <here, the cell will harvest energy from coupled reactions at 6 steps out of 9 total (compare this to glycolysis)> (A) Harvesting high energy electrons (:H￿ ions): move once through the cycle [Fig. 13-11] (1) Recall that pyruvate (3C) is the product of glycolysis. It enters the TCA cycle in an indirect way: it combines with coenzyme A (“CoA”) t...
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