If there is no o2 available the entire chain will be

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Unformatted text preview: been passed to the end of the electron transport chain, the final donor is cytochrome C and the final acceptor is molecular oxygen. If there is no O2 available, the entire chain will be blocked and electron transport will cease. This is because the passage of successive electron pairs down the chain depends upon the reoxidization of each element of the chain - an electron carrier that cannot give up its electrons cannot in turn accept another pair. If O2 is not available to accept electrons from the last element in the chain, the whole chain backs up with every element in its reduced form, and stops functioning. (B) ATP synthesis by the mitochondrial ATP synthase (figs 14-11 thru -13; DVD 14-3) (1) The energy of the proton gradient is harnessed by a special H+ transporter in the IMM. This transporter is ATP synthase, and it is a multi-subunit protein (see figure below). It consists essentially of a complex, shifting transmembrane channel that allows H+ to move (under normal conditions) from the IMS back across the IMM into the matrix, and couples that favorable movement to ATP synthesis. It is, in effect, a rotary motor that spins in the plane of the membrane as H+ flow through. How cool...
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