Catalyzed by a multienzyme complex called pyruvate

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Unformatted text preview: re oxygen. Pyruvate is converted to acetyl-CoA • Pyruvate must first be transported to the mitochondria. • Catalyzed by a multienzyme complex called pyruvate dehydrongenase. • Contains 3 different enzymes and 60 polypeptide chains. • Intermediates are ‘passed’ from one enzyme to another (proximity and orientation of the active sites limits diffusion) The Citric Acid Cycle • Both sugars and fats enter the TCA cycle as acetyl CoA • Fatty acids are converted to acetyl CoA in the mitochondria by a series of four enzymes. Energy production from the...
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This note was uploaded on 06/30/2012 for the course PCB 3023 taught by Professor Sikorski during the Spring '07 term at University of South Florida - Tampa.

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