bio 102 lecture 1-28 - 1/28/08- Cells I: Introduction...

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1/28/08- Cells I: Introduction (reading: Ch 3: 38-43; Ch 4: 58, 64-71) Outline Introduction to cells HIV life cycle Cell membrane function Basic cell structure HIV Life cycle 1. Virus binds receptors on cell membrane, and enters cell. Enzymes remove proteins of viral capsid. 2. RT (reverse transcriptase) catalyzes formation of DNA complementary to viral RNA. 3. New DNA strand serves as a template for complementary DNA strand. 4. Double stranded DNA is incorporated into host cell’s genome. 5. Viral genes transcribed into mRNA. Some viral DNA copied as the RNA genome for virions. 6. mRNA (messenger RNA) translated into HIV proteins in cytoplasm. 7. Capsids (protein coats) surround new viral RNA genomes. 8. New viruses bud from host cell. Questions How does HIV get into a cell? Why aren’t cells permeable to other things? Why are cells “alive” and viruses not? How is virus structure different from cell structure?
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bio 102 lecture 1-28 - 1/28/08- Cells I: Introduction...

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