Chapter 13 Outline - - Weight regulation normal after a...

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Chapter 13: Biological Models Insulin and Hunger 1. Cephalic phase: anticipation of glucose arrival 2. Digestive phase: food enters stomach and intestines, causes gut hormones to be released 3. Absorptive phase: glucose in bloodstream, detected by glucodetectors in liver, signal for insulin release. - Nerve impulses from liver go to vagus nerve, synapses in nucleus of solitary tract. - Insulin helps determine satiety, but there is more, people with diabetes can still be hungry. Hypothalamus and Hunger - Hypothalamus controls hunger - VMH lesions cause obesity - LH lesions cause starvation
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Unformatted text preview: - Weight regulation normal after a while. The Arcuate Nucleus-Leptin: made by fat cells, signal satiety in the brain, defects cause obesity-Ghrelin: secreted by endocrine cells of stomach into bloodstream, appetite stimulant, decreases after eating.-Peptide YY 3-36 : secreted by small and large intestine, reduces appetite, opposes ghrelin.-Neuropeptide Y/Agouti-Related Peptide: Stimulates appetite, reduces metabolism. Activated by ghrelin, inhibited by Peptide YY 3-36-POMC/CART: inhibit appetite, increase metabolism. Activated by leptin....
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