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Liberty UniversityMaster of Molecular MedicineMSCI 500Tumor Angiogenesis- A Chapter SummaryCaelan HuffID: L28352446September 20, 2020Words: 641
Tumor growth is a process that is constantly being explored and new discoveries are always being made, but some of the discoveries don’t always ring true. One thing that is true of tumor proliferation is that it must have a vascular network to support the flow of nutrients, immune cells, and other elements that are key to survival. This lymphatic vasculature is formed during a process called angiogenesis; a tumor is able to overcome the normal angiogenesis of healthy cells which in turn causes cancer cells to rapidly grow. Several growth factors contribute to the success of angiogenesis, while many anti-angiogenic factors try to combat the spreading network that fuels a tumor. Throughout chapter 3 of The Molecular Basis of Cancer, Mendelson et al. discuss the vascular development in normal and tumor cells, pro-angiogenic factors that encourage angiogenesis, and the anti-angiogenic factors that inhibit vessel cell growth.1