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Unformatted text preview: s, an individual with mulKple mutaKons is more likely to be eliminated than an individual with a few deleterious mutataKons MutaKon Load and MutaKon Rate • Our best informaKon about the eﬀects of mutaKons on the populaKon load come from areas around nuclear disaster sites, such as Chernobyl • Chernobyl was a nuclear power plant in the Ukraine that exploded at 1:23AM on April 26, 1986 • RadioacKve parKcles swept across the Ukraine, Belarus, Western Russia, and, eventually throughout the enKre Western Hemisphere • Millions of people were exposed to radiaKon in varying doses • Increases in somaKc mutaKons, leading to increased rates of cancer were immediately observed • Moreover, germ line mutaKons, apparently recessive, are now being observed at much higher levels in the grandchildren of exposed people • Recent surveys indicate that mutaKonal load is higher in insects, birds, and other wildlife populaKons in the area Fate of a new mutaKon • In real life, most new mutaKons are lost within a few generaKons • What is the probability that a new mutant allele will be lost at any Kme in the future? Fate of a new mutaKon AA Aa AA AA AA AA • When a new mutaKon (a) arises, the individual carrying it will necessar...
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This note was uploaded on 11/20/2012 for the course BIO bio3124 taught by Professor Rezanokhbeh during the Spring '11 term at University of Ottawa.
- Spring '11