Unformatted text preview: ily mate with a AA individual • Assuming an average number of oﬀspring per maKng as 2 (keeping with a stable populaKon model), the probability that the ﬁrst oﬀspring will not receive the novel a allele is ½, and (independently) the probability that the 2nd oﬀspring will not receive the novel a allele is also ½. • Thus, the probability that the allele a will be lost in the next generaKon is: 1 2 1
Pr(loss) = = 2 4 Fate of a new mutaKon • From this it is straighqorward to extrapolate that if a maKng produces k oﬀspring, the probability of loss of the allele is 1 k
Pr(loss | k ) = 2 • Assuming that k is a random variable that follows a Poisson DistribuKon, and the average family size is two, then the probability that a family will be k is: € e−2 2 k
Pr(K = k ) =
k! • Thus, using the law of total probability, the pr...
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This note was uploaded on 11/20/2012 for the course BIO bio3124 taught by Professor Rezanokhbeh during the Spring '11 term at University of Ottawa.
- Spring '11