L18_NPB_101

L18_NPB_101 - Lecture 18 SmartSite Lecture 18 Notes...

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Lecture’18 SmartSite: Lecture’18’Notes Announcements: Grades’&’Key’Posted’on’ SmartSite Class’Mean’=’20.7 Std’Dev’=’4.1 Remember’to’Check’Smartsite’ for’your’grade’accuracy’ Reading’(Recommended): Relevant’por±ons’Chapter’8 Review - Skeletal’muscle Muscle - Smooth’muscle - Cardiac’muscle 1
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REV:’Muscle ExcitaNon-contracNon’coupling ±MJ,’T-Tubule,’SR,’Ca 2+ ,’RelaxaNon Mechanics’of’contracNon’(number’of’cross’bridges) Force-Velocity’curve Length-Tension’relaNonship RegulaNon’of’contracNon’force SummaNon’of’Twitchs Motor’unit’size’&’number’of’motor’units Types’of’skeletal’muscle’²bers Fast’vs.’Slow 2
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ExcitaNon- ContracNon’Coupling AP from motorneuron i Ach End Plate Poten2al (EPSP) i AP on muscle Fber cell membrane (sarcolema) i AP conducted over sarcolema/T-tubule i Excita2on of Sarcoplasmic Re2culum (SR) i (increase P Ca ) Di±usion of Ca 2+ out of SR and into myoFbril i Ca 2+ binds with Troponin and shi²s Tropomyosin i Ac2n ac2vated i Ac2n-Myosin cross bridge i Myosin power stroke i FORCE RELAXATION Di±usion of Ca 2+
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L18_NPB_101 - Lecture 18 SmartSite Lecture 18 Notes...

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