This preview shows page 1. Sign up to view the full content.
Unformatted text preview: ng” chromosomes using large
fluorescently labeled probes against multiple
sequences on the chromosomes http://www.chrombios.com/cms/website.php?id=/en/index/aboutfish/multicolor.htm Can FISH with a fluorescent probe against each
of the genetic regions below detect the
diseases associated with the gene?
FGFR3 – Achondroplasia
Chromosome 21 – Down syndrome
Factor VIII - Hemophilia Down syndrome (DS)
- first described in 1866 by English physician John Langdon
- Affects 1 in 700 newborns
• Upward slant to eyes, small, flattened nose,
• Small mouth, making tongue appear large.
• Short neck.
• Small hands...
View Full Document
- Spring '06