Lecture9DownSyndrome_000

Com20111211healthresearchhemophiliab gene therapy

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Unformatted text preview: normal http://www.nytimes.com/2011/12/11/health/research/hemophiliab-gene-therapy-breakthrough.html?_r=0 Banding patterns on human mitotic chomosomes Giemsa stain: regions of condensed chomatin (darker - G bands) and less condensed chromatin (lighter - R bands) human chromosome 4 at varying resoluEons due to exact mitoEc stage, (or degrees of spreading  ­ squashing  ­ stretching) Clicker Q On Dec. 1, 1999, the sequencing of the first complete human chromosome was completed. Which chromosome was sequenced first? A.  B.  C.  D.  Chr. 1 Chr. 16 Chr. 22 Chr. X Labeling different chromosomes with fluorescent in situ hybridization (FISH) allows (relative) amateurs to do human cytogenetic analyses FISH to show trisomy 21 Trisomy 21 and normal chromosome number for 13 Two green chromosome 13 probe signals indicate the normal chromosome 13 number and three pink chromosome 21 probe signals indicate trisomy 21 DE Zhang “Painti...
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This note was uploaded on 01/07/2013 for the course BIMM 100 taught by Professor Pasquinelli during the Spring '06 term at UCSD.

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