Lecture 6 Supplement

Lecture 6 Supplement - example of “chemical” polarity...

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Additional information on DNA structure for the lecture on January 16, 2008
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From Dr. Cardullo’s lecture on April 24!
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example of “chemical” polarity
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Watson and Crick (1953)
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Rosalind Franklin X-Ray diffraction 2 r = 20 nm
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2 r = 20 nm
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The structure of DNA Chargaff (1947) %A, %C, %G, %T unique to each species %A = %T %G = %C (Chargaff’s rules) purines pyrimidines
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They reasoned that H-bonds could hold the chains together A T G C base pairs are flat
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DNA strands are antiparallel
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Unformatted text preview: example of “chemical” polarity The Double Helix 5’ 3’ 3’ 5’ 10 base pairs per turn Summary of structural levels • sugar-phosphate backbone • nitrogenous bases A, C, G, T • double helix = secondary structure • antiparallel chains • bases held together by H-bonds • A pairs with T, G pairs with C • information: order of the bases = primary structure Fig 16.5...
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Lecture 6 Supplement - example of “chemical” polarity...

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